Spike-triggered Neural Characterization.

Odelia Schwartz, Jonathan W. Pillow, Nicole C. Rust, and Eero P. Simoncelli.

Journal of Vision, 2006.

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Neural responses are commonly described using linear receptive fields. This may be generalized to a response model that operates with a small set of linear filters whose outputs are nonlinearly combined to determine the instantaneous firing rate. Spike-triggered average and covariance analyses can be used to estimate the filters and nonlinear combination rule from extracellular experimental data. We describe this methodology, demonstrating it with simulated model neuron examples that emphasize practical issues that arise in experimental situations.
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